KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
22.42
Human Site:
T929
Identified Species:
49.33
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
T929
S
Q
R
I
L
R
R
T
A
S
A
P
T
K
S
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
T913
G
D
R
I
L
R
R
T
A
S
A
P
A
K
G
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
T936
S
Q
R
L
L
R
R
T
A
S
A
P
T
K
S
Dog
Lupus familis
XP_546733
1387
151432
T913
S
Q
R
L
L
R
R
T
A
S
A
P
T
K
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
T1010
S
Q
R
L
L
R
R
T
A
S
A
P
T
K
S
Rat
Rattus norvegicus
Q62688
1096
122754
S653
S
A
M
R
I
D
S
S
N
L
N
P
Q
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
L194
L
N
G
Y
I
S
A
L
L
K
G
C
R
C
L
Frog
Xenopus laevis
Q32NH8
758
87399
R315
Y
L
M
E
D
Q
I
R
G
Q
S
S
I
E
G
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S341
K
D
Q
V
T
S
A
S
S
T
E
P
Y
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
Y875
A
L
A
N
P
I
K
Y
Q
S
E
L
E
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S1137
H
I
L
R
L
G
I
S
P
S
Q
I
I
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
73.3
93.3
93.3
N.A.
93.3
13.3
N.A.
N.A.
0
0
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
73.3
100
100
N.A.
100
26.6
N.A.
N.A.
6.6
20
40
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
19
0
46
0
46
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
0
19
0
0
10
10
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
19
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
10
0
0
10
0
0
10
0
10
0
0
0
19
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
19
19
10
19
0
0
0
0
10
19
10
0
% I
% Lys:
10
0
0
0
0
0
10
0
0
10
0
0
0
55
0
% K
% Leu:
10
19
10
28
55
0
0
10
10
10
0
10
0
0
10
% L
% Met:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
10
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
10
0
0
64
0
0
0
% P
% Gln:
0
37
10
0
0
10
0
0
10
10
10
0
10
10
0
% Q
% Arg:
0
0
46
19
0
46
46
10
0
0
0
0
10
0
19
% R
% Ser:
46
0
0
0
0
19
10
28
10
64
10
10
0
0
37
% S
% Thr:
0
0
0
0
10
0
0
46
0
10
0
0
37
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
10
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _